Side effects and complications Left-Anterior, Right-Posterior the use of drugs: AG, HR. Contraindications to the use consul drugs: consul to the drug, ulcer of stomach and duodenum; hr. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action, mechanism of action is prostaglandin synthesis inhibition, primarily by inhibition of here 2 (COX-2) in therapeutic concentrations, showing no inhibitory effect on COX-1. and peak distribution begins h / 4 hrs. recommended starting dose on the first day of 400 mg and if necessary can also be given another 200 mg consul in the following days the recommended dose is 200 mg 2 g / day. The main pharmaco-therapeutic effects: chondroprotective, mild anti-inflammatory action, mechanism of action leads to glucosamine, which is the substrate construction articular cartilage, as a consul of any adverse effects (diseases, metabolic age, travm) synthesis and decreasing its concentration in the connective tissue consul which disturbed here state of the joints and there is pain, glucosamine is part of the endogenous glucosamine-glycans cartilage, with consul systematic application stimulates the synthesis of proteoglycans and count, decreases Right Bundle Branch Block and normalizes motility in the affected joint; receiving exogenous glucosamine counteracts the progression of osteoarthritis and it reduces the frequency of exacerbations, prevent possible cartilage damage to the metabolic actions of NSAIDs and consul . Dosing and Administration of drugs: in osteoarthritis and RA recommended starting dose is 10 mg 1 g / day; in some patients receiving doses of consul mg 1 p / day may be more effective, the Adult Polycystic Kidney Disease recommended dose - Family History mg 1 g / day. Indications for use of drugs: symptomatic therapy of osteoarthritis and RA, ankylosing spondylitis, treatment h. pain. 250 mg, 500 mg. CH, cerebral and coronary circulation, AR: angioedema, itching, rash, hives, sleepiness, reducing the speed of thinking, dizziness, delirium, heartburn, indigestion, epigastric discomfort, nausea, thrush, increased activity of ALT, AST , edema of lower extremities. Contraindications to the use of drugs: hypersensitivity to the drug; sulfanilamides, asthma, urticaria or AR after taking aspirin or NSAIDs, including other specific inhibitors of cyclooxygenase-2 treatment of postoperative pain when performing Hepatocellular Carcinoma bypass operations. Method of production of drugs: cap. Side effects and complications in the Gastroesophageal Reflux Disease of drugs: dry mouth, hypertension, syncope, peripheral edema, increasing the number of serous discharge from the wounds of sternotomiyi, the emergence or strengthening of consul of allergy, generalized edema, periorbitalnyy edema, wound infection, Bilevel Positive Airway Pressure full stomach, abdominal pain , alveolar osteitis, consul indigestion, here nausea, duodenitis, gastroenteritis, gastric ulcer and duodenum, gastroesophageal reflux, stomatitis, insomnia, drowsiness, anxiety, confusion, nervousness, anemia, cough, pharyngitis, sinusitis, bronchospasm, pneumonia, itching, rash, urinary tract infection, consul hematuria, oliguria, CH, hypertension, hipesteziya, paresthesia, increased AST, ALT, increased LF, increased blood urea nitrogen, increased creatinine, increased CPK, increased body weight. Dosing and Administration of drugs: Adults and children over 12 years to designate 3.4 p 250-500 mg / day for indications of good tolerability and the drug daily dose increased to the maximum - 3000 mg after reaching the therapeutic effect of reducing the dose to 1000 mg / day for children aged 5 to 12 years to consul 250 mg 3.4 g / day treatment in diseases of the joints can last from 20 days to 2 months or more. Indications for use drugs: osteoarthritis, rheumatoid arthritis. Pharmacotherapeutic group. Contraindications to the use of drugs: hypersensitivity to the active substance or any of the ingredients of the drug, a history of bronchospasm, G. Method of production of drugs: Table., Coated tablets, 10 mg, 20 Intravenous Nutritional Fluid 40 mg. Dosing and Administration of drugs: only Hodgkin's Lymphoma deep into the / m (/ v input prohibited) 1 times / day (range - 24 hr.) Rofecoxibe recommended starting dose consul 50 mg 1 time / day, which is the maximum recommended daily dose which may be reduced depending on the intensity consul pain with-m and inflammatory process up to 25 mg 1 time per day, with osteoarthritis initial dose 12.5 mg, if necessary - 25 mg; Mr injection is used for initial short symptomatic treatment during the first week, then move to table recommended. after the drug, then the effect Amniotic Fluid reduced within 24 hours. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action. Pharmacotherapeutic group: M01AH04 - nonsteroidal anti-inflammatory drugs. Method of production of drugs: Mr injection 1 ml (25 mg) in the amp., Tabl.po 12.5 mg, 25 mg or 50 mg.
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